Slightly OT: I've never heard of Skia before, but a few years ago I was trying to find a good vector graphics solution for realtime video games... can it be used for that?
It has a GPU back end so it can be pretty fast, but it is still focused on very high quality antialiased rendering so it isn't crazy fast. Apps like Chrome and Sublime don't repaint the entire screen every frame or when scrolling, only the parts that change, so they can afford high quality.
You probably could but you're having a bad time compiling and building Skia. It uses a peculiar build system (that is used throughout the chromium ecosystem). It does have a performance in mind and even comes with a tool (nanobench) to measure perf.
That being said for a game you'd probably be better off with a higher level engine that also manages the scene graph, spatial sorting etc things for you unless you want to work on that part yourself.
