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> Fully curing mice is the baseline for a treatment to even be considered for further evaluation

If it never works as well if at all in humans, maybe mice are too different?



It’s not that. The tumors they create in mice are just really fragile compared to natural tumors. Natural tumors that actually cause problems have probably grown for years and learned to avoid immune responses. They’re not densely packed and easy to get into all the parts.

This kind of treatment triggers an immune response, which the model tumors have never had to fight before. So it’s just an easy target.




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